Hematometra associated with estrogen replacement therapy.

Abstract

We have described two cases of hematometra occurring after initiation of estrogen replacement therapy. In both cases, cervical stenosis had developed during a prolonged period of hypoestrogenism. After initiation of sequential estrogen/progestin therapy, the stenosis prevented menstrual flow, and sonography revealed an asymptomatic hematometra in both cases. Based on these cases, we recommend doing a baseline evaluation of cervical patency before initiating estrogen replacement therapy in women who have been menopausal for a substantial length of time.

• Authors: P C Sacks, R J Falk
• Journal: Southern medical journal (South Med J) Vol. 86 Issue 7 Pg. 842-3 (Jul 1993) ISSN: 0038-4348 [Print] United States
• PMID: 8322096 (Publication Type: Case Reports, Journal Article)

Chemical References

• Estrogens

Topics

• Aged
• Constriction, Pathologic
• Estrogen Replacement Therapy (adverse effects)
• Estrogens (deficiency)
• Female
• Hematometra (etiology)
• Humans
• Menopause
• Middle Aged
• Time Factors
• Uterine Cervical Diseases (complications, pathology)