[The contrast enhancement of brain and spinal cord tumors using Gd-DTPA in magnetic resonance tomography with an extra-low magnetic-field intensity].

Abstract

The contrasting agent Gd-DTPA (Magnevist, Schering AG, Germany) was tested when used in magnetic resonance tomography using extra-low (0.04 T) magnetic field intensity in 68 patients with various brain and spine tumors. The agent was injected intravenously in a dose of 0.1 mmol/kg. No complications were found. The tests showed its high efficiency in the diagnosis of brain neoplasms (particularly in malignant intracerebral disorders, meningiomas and neurinomas). Benign astrocytomas induced no noticeable signal intensification on post-contrasting T1-weighed tomograms. In all cases of spinal tumors, the application of Gd-DTPA could specify the extent of tumor invasions, the presence of cysts and identify accessory tumor nodes in one case.

• Authors: V N Kornienko, I N Pronin, A M Turkin, L M Fadeeva
• Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (Zh Vopr Neirokhir Im N N Burdenko) 1993 Oct-Dec Issue 4 Pg. 13-7 ISSN: 0042-8817 [Print] Russia (Federation)
• Vernacular Title: Kontrastnoe usilenie opukholeĭ golovnogo i spinnogo mozga s pomoshch'iu Gd-DTPA pri magnitno-rezonansnoĭ tomografii so sverkhnizkoĭ napriazhennost'iu magnitnogo polia.
• PMID: 8296501 (Publication Type: English Abstract, Journal Article)

Chemical References

• Contrast Media
• Organometallic Compounds
• Pentetic Acid
• Gadolinium
• Gadolinium DTPA

Topics

• Adult
• Aged
• Brain (pathology)
• Brain Neoplasms (diagnosis)
• Contrast Media
• Drug Evaluation
• Female
• Gadolinium
• Gadolinium DTPA
• Humans
• Magnetic Resonance Imaging (instrumentation, methods)
• Male
• Middle Aged
• Organometallic Compounds
• Pentetic Acid (analogs & derivatives)
• Sensitivity and Specificity
• Spinal Cord (pathology)
• Spinal Cord Neoplasms (diagnosis)