The effects of a silica dentifrice containing Triclosan and zinc citrate on supragingival plaque and calculus formation and the control of gingivitis.

Abstract

A double blind, 7-month parallel clinical study was conducted to determine the effect of a dentifrice containing 0.3 per cent Triclosan and 0.75 per cent zinc citrate in a 0.8 per cent sodium monofluorophosphate/silica base on supragingival plaque, gingivitis and supragingival calculus formation, compared to a 0.8 per cent monofluorophosphate/silica control dentifrice. The results of this clinical study demonstrate that the use of the Triclosan/zinc citrate dentifrice over a 7-month period provided a statistically significant and clinically relevant benefit in controlling gingivitis, compared to a control dentifrice. Supragingival plaque and calculus levels were also significantly reduced in comparison to the effects of a control dentifrice.

• Authors: B Svatun, C A Saxton, E Huntington, D Cummins
• Journal: International dental journal (Int Dent J) Vol. 43 Issue 4 Suppl 1 Pg. 431-9 (Aug 1993) ISSN: 0020-6539 [Print] England
• PMID: 8282426 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Citrates
• Dentifrices
• Phosphates
• fluorophosphate
• Citric Acid
• Triclosan
• Silicon Dioxide
• Zinc
• Fluorides

Topics

• Adult
• Citrates (administration & dosage, therapeutic use)
• Citric Acid
• Dental Calculus (prevention & control)
• Dental Plaque (prevention & control)
• Dental Plaque Index
• Dentifrices
• Double-Blind Method
• Female
• Fluorides (administration & dosage, therapeutic use)
• Gingival Hemorrhage (prevention & control)
• Gingivitis (prevention & control)
• Humans
• Male
• Oral Hygiene
• Periodontal Index
• Phosphates (administration & dosage, therapeutic use)
• Silicon Dioxide
• Time Factors
• Toothbrushing
• Triclosan (administration & dosage, therapeutic use)
• Zinc (administration & dosage, therapeutic use)