Abstract | OBJECTIVES: BACKGROUND: METHODS: RESULTS: Sixteen (27%) of the 60 dogs in which the protocol was attempted developed spontaneous ventricular fibrillation 21 min after ligation and were included in the study. Lidocaine and epinephrine plus five direct-current countershocks succeeded in converting ventricular fibrillation in one dog (6%). The other 15 dogs were randomized to group I (8 dogs) or group II (7 dogs). Defibrillation was achieved in one of the eight dogs in group I and in six of the seven dogs in group II (p < 0.005). CONCLUSIONS:
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Authors | M I Anastasiou-Nana, J N Nanas, S N Nanas, A Rapti, A Poyadjis, S Stathaki, S D Moulopoulos |
Journal | Journal of the American College of Cardiology
(J Am Coll Cardiol)
Vol. 23
Issue 1
Pg. 253-8
(Jan 1994)
ISSN: 0735-1097 [Print] United States |
PMID | 8277089
(Publication Type: Journal Article)
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Chemical References |
- Lidocaine
- Amiodarone
- Epinephrine
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Topics |
- Amiodarone
(administration & dosage, pharmacology, therapeutic use)
- Animals
- Disease Models, Animal
- Dogs
- Electric Stimulation
- Epinephrine
- Female
- Heart Conduction System
(drug effects)
- Heart Rate
(drug effects)
- Hemodynamics
- Injections, Intravenous
- Lidocaine
- Male
- Myocardial Infarction
(drug therapy, physiopathology)
- Ventricular Fibrillation
(drug therapy)
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