[Sphenocavernous localization of meningeal neurosarcoidosis. Apropos of a case and review of the literature].

Abstract

The authors report on the case of a 32 year old woman treated with prednisone and diphenylsulfon for a multi-visceral sarcoidosis; headache and progressive oculomotor paralysis revealed an expansive lesion of the left cavernous sinus extending to the temporal fossa. C.T. scan, M.R.I., and angiographic data as well as the intra-operative findings evoked the diagnosis of meningioma. Pathological findings showed an epithelioid and gigantocellular granuloma without caseous necrosis, corresponding to a sarcoidosic lesion. After the operation, the increase of steroid doses was followed by a complete regression of the tumoral remnants, and total clinical recovery. In a patient having a previously diagnosed sarcoidosis with evidence of an intracranial tumor mimicking a meningioma, steroids should be first prescribed. Efficacy of steroids on sarcoid granulomas is often dramatic; surgical approach would be discussed in case of ineffective steroid therapy, of persisting questionnable diagnosis, and of tumoral threatening compression.

• Authors: F Nataf, B Devaux, C Lamy, C Fallet-Bianco, F X Roux
• Journal: Neuro-Chirurgie (Neurochirurgie) Vol. 39 Issue 2 Pg. 128-31 ( 1993) ISSN: 0028-3770 [Print] France
• Vernacular Title: Localisation sphéno-caverneuse de la neurosarcoïdose méningée. A propos d'un cas et revue de la littérature.
• PMID: 8247216 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Adrenal Cortex Hormones

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Adult
• Cavernous Sinus
• Central Nervous System Diseases (diagnostic imaging, etiology, pathology)
• Diagnosis, Differential
• Female
• Humans
• Meningeal Neoplasms (diagnosis)
• Meninges (diagnostic imaging, pathology)
• Meningioma (diagnosis)
• Sarcoidosis (complications, drug therapy, pathology)
• Tomography, X-Ray Computed