HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

New assay of protective activity of Rocky Mountain spotted fever vaccines.

Abstract
Areas under the fever curves of guinea pigs inoculated with Rocky Mountain spotted fever vaccine over a restricted dose range and infected with a standardized dose of Rickettsia rickettsii varied linearly with log10 dose of vaccine. A calculator was programmed to plot fever curves and calculate the vaccine dose that reduced the fever of infected animals by 50%.
AuthorsR L Anacker, R F Smith, R E Mann, M A Hamilton
JournalJournal of clinical microbiology (J Clin Microbiol) Vol. 4 Issue 3 Pg. 309-11 (Sep 1976) ISSN: 0095-1137 [Print] United States
PMID823177 (Publication Type: Journal Article)
Chemical References
  • Rickettsial Vaccines
  • Vaccines
Topics
  • Animals
  • Body Temperature
  • Drug Evaluation, Preclinical
  • Guinea Pigs
  • Injections, Intraperitoneal
  • Male
  • Rickettsia rickettsii (immunology)
  • Rickettsial Vaccines (administration & dosage)
  • Rocky Mountain Spotted Fever (prevention & control)
  • Vaccines (administration & dosage)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: