HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[The automatic implantable cardioverter-defibrillator for prevention of sudden heart death in children and adolescents].

Abstract
Little experience exists with the automatic implantable cardioverter-defibrillator in the pediatric population. Since 1990, an automatic implantable cardioverter defibrillator was implanted in four young patients (mean age 15.8 years, mean body weight 53.3 kg) with life-threatening ventricular tachyarrhythmias at our institution. In three patients, a cardiac anomaly was evident (dilated cardiomyopathy, status post Rastelli operation for complex transposition of the great arteries, status post atrial switch for transposition of the great arteries), the last patient had a normal cardiac anatomy. Indications for implantation were resuscitation from documented hypotensive ventricular tachycardia in one patient and recurrent syncope of suspected cardiac origin in the remaining three patients. At preimplantation electrophysiological study, all four patients had inducible ventricular tachycardia and/or ventricular fibrillation. At implantation of the cardioverter defibrillator in the operating theatre, the ventricular tachyarrhythmias were again induced and terminated reliably by the device. After a mean follow-up of 13 months, three of the four patients had appropriate discharges without syncope or resuscitation. The automatic implantable cardioverter-defibrillator appears to be a feasible and effective therapy also in pediatric patients for prevention of sudden cardiac death due to ventricular tachyarrhythmias.
AuthorsT Paul, I Luhmer, H J Trappe, H Klein, H G Fieguth, C Brauer, U Scharpwinkel, H C Kallfelz
JournalZeitschrift fur Kardiologie (Z Kardiol) Vol. 82 Issue 8 Pg. 466-73 (Aug 1993) ISSN: 0300-5860 [Print] Germany
Vernacular TitleDer automatische implantierbare Kardioverter-Defibrillator zur Verhütung des plötzlichen Herztodes bei Kindern und Jugendlichen.
PMID8212779 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Adolescent
  • Cardiac Pacing, Artificial
  • Cardiomyopathy, Dilated (complications, genetics, physiopathology)
  • Child
  • Death, Sudden, Cardiac (prevention & control)
  • Defibrillators, Implantable
  • Electrocardiography
  • Female
  • Follow-Up Studies
  • Heart Conduction System (physiopathology)
  • Heart Defects, Congenital (complications, physiopathology)
  • Humans
  • Male
  • Tachycardia, Ventricular (etiology, physiopathology, therapy)
  • Ventricular Fibrillation (physiopathology, therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: