[Changes in the cerebral hemodynamics during Rohypnol anesthesia in neurosurgical patients].

Abstract

Intracranial pressure, cerebral perfusion pressure, and intracerebral blood volume changes were observed in 43 patients with volumetric intracranial processes (intracranial hematomas, tumors) during general rohypnol anesthesia. Intracranial and cerebral perfusion pressures were found to correlate with intracerebral blood volume. Rohypnol anesthesia decreased intracranial pressure by 25% due to reduced arterial blood influx into the head, mechanisms responsible for autoregulation of cerebral circulation being intact.

• Authors: A V Gribkov, L M Bakunin, N Iu Rufova
• Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (Zh Vopr Neirokhir Im N N Burdenko) 1994 Apr-Jun Issue 2 Pg. 29-32 ISSN: 0042-8817 [Print] Russia (Federation)
• Vernacular Title: Izmeneniia tserebral'noĭ gemodinamiki pri narkoze rogipnolom u neĭrokhirurgicheskikh bol'nykh.
• PMID: 8209591 (Publication Type: English Abstract, Journal Article)

Chemical References

• Flunitrazepam

Topics

• Adult
• Aged
• Anesthesia, General (methods)
• Anesthesia, Intravenous (methods)
• Brain (drug effects, physiopathology, surgery)
• Brain Injuries (physiopathology, surgery)
• Cerebrovascular Circulation (drug effects)
• Flunitrazepam
• Hemodynamics (drug effects)
• Humans
• Intracranial Pressure (drug effects)
• Middle Aged
• Supratentorial Neoplasms (physiopathology, surgery)