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Collagenous colitis and lymphocytic colitis.

Abstract
Collagenous and lymphocytic colitis are newly recognized causes of chronic watery diarrhea that typically affect middle-aged patients. Although endoscopic studies are normal, inflammatory changes and (in the case of collagenous colitis) collagen deposition occur histologically in the colonic mucosa. The pathogenesis of these disorders remains a mystery, but the possible causes are intriguing. Patients may experience spontaneous remissions and relapses, but treatment with sulfasalazine or prednisone is usually effective for patients with distressing symptoms.
AuthorsJ M Zeroogian, S Chopra
JournalAnnual review of medicine (Annu Rev Med) Vol. 45 Pg. 105-18 ( 1994) ISSN: 0066-4219 [Print] United States
PMID8198370 (Publication Type: Journal Article, Review)
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Colitis (diagnosis, drug therapy, etiology, pathology)
  • Collagen Diseases (diagnosis, drug therapy, etiology, pathology)
  • Female
  • Humans
  • Lymphocytes (pathology)
  • Male
  • Middle Aged

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