[A case of retroperitoneal lymph node recurrence with gallbladder cancer responding to UFT and CDDP combination chemotherapy].

Abstract

A 64-year-old women with gallbladder cancer was treated by extended cholecystectomy and regional lymph node dissection. At 18 months after surgery, an enlarged retroperitoneal lymph node due to recurrence was demonstrated by computed tomography, and CEA and CA 19-9 showed high serum levels. Combination chemotherapy consisting of UFT administered orally at 200 mg daily and CDDP infused at 40 mg/m2 every 2 weeks was performed in 3 courses. After this therapy, the retroperitoneal lymph node was undetectable by computed tomography and both CEA and CA 19-9 decreased to within normal levels. It appeared that this chemotherapy is effective for gallbladder cancer.

• Authors: T Kotoh, S Arima, K Futami
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 21 Issue 6 Pg. 881-4 (May 1994) ISSN: 0385-0684 [Print] Japan
• PMID: 8185350 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Tegafur
• Uracil
• Cisplatin

Topics

• Adenocarcinoma (drug therapy, pathology, surgery)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cisplatin (administration & dosage)
• Female
• Gallbladder Neoplasms (drug therapy, pathology, surgery)
• Humans
• Lymph Node Excision
• Lymph Nodes (pathology)
• Lymphatic Metastasis
• Middle Aged
• Tegafur (administration & dosage)
• Uracil (administration & dosage)