Hypophyseal non-Hodgkin's lymphoma presenting with clinical panhypopituitarism successfully treated with chemotherapy.

Abstract

A patient is described with a testicular Non-Hodgkin's Lymphoma (NHL) presenting with panhypopituitarism caused by a hypophyseal localization. A 67Gallium scintigraphy showed avid uptake in the hypophyseal region. Obviously 67Gallium could reach the tumor, by the intravenous route, which was the reason to treat the patient with intravenous chemotherapy. A complete remission was induced, which seems to be lasting (+25 months). As far as we know this is the first report of panhypopituitarism caused by a hypophyseal NHL in the hypophysis and successfully treated by intravenous chemotherapy.

• Authors: A R Jonkhoff, P C Huijgens, W O Schreuder, G J Teule, J J Heimans
• Journal: Journal of neuro-oncology (J Neurooncol) Vol. 17 Issue 2 Pg. 155-8 (Aug 1993) ISSN: 0167-594X [Print] United States
• PMID: 8145058 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Humans
• Hypopituitarism (etiology)
• Lymphoma, Non-Hodgkin (complications, diagnosis, diagnostic imaging, drug therapy)
• Male
• Pituitary Neoplasms (complications, diagnosis, diagnostic imaging, drug therapy)
• Radionuclide Imaging