[Failure of intravenous immunoglobulins in certain systemic diseases. 5 cases].

Abstract

Human polyvalent immunoglobulins administered intravenously have shown to be effective in some immune diseases. We administered high dose-IV Ig (2g/kg/session) in five patients with severe chronic systemic diseases. Their condition did not improve, except in one case where a transient response was noticed. Considering the inconsistent results and high cost of IV Ig, double blind studies are required to determine the conditions in which high dose IV Ig may be more effective than conventional treatments.

• Authors: P Bahadoran, M De Bandt, M Echard, B Jarrousse, L Guillevin
• Journal: Presse medicale (Paris, France : 1983) (Presse Med) Vol. 22 Issue 25 Pg. 1175-8 (Sep 04 1993) ISSN: 0755-4982 [Print] France
• Vernacular Title: Echec des immunoglobulines intraveineuses au cours de certaines maladies systémiques. 5 observations.
• PMID: 8105460 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adult
• Cryoglobulinemia (drug therapy)
• Female
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Male
• Middle Aged
• Polyarteritis Nodosa (drug therapy)
• Polymyositis (drug therapy)
• Retrospective Studies
• Time Factors