Abstract |
The therapeutical efficiency and the undesirable effects of Nalbuphine administered to control postoperative pain were compared. Two groups of patients were studied: one group received 10 mg endovenously every 4 h during the first 12 h of the postoperative phase and every 6 h during the following 12 h while the other group received 20 mg with the same intervals. The following variants were evaluated: pain, systolic arterial tension, cardiac frequency, respiratory frequency and undesirable effects. After statistical analysis, a similarity in both groups was confirmed for pain, systolic arterial tension, cardiac frequency, while a significant difference was found in two of the undesirable effects: sedation and sweating. In conclusion, the 10 mg dose is as effective as that of 20 mg to control pain and has less unwanted effects.
|
Authors | D Bagilet, J Despósito, A Giovannoni, E Javkin |
Journal | Medicina
(Medicina (B Aires))
Vol. 53
Issue 6
Pg. 503-6
( 1993)
ISSN: 0025-7680 [Print] Argentina |
Vernacular Title | Nalbufina. Comparación de dos regímenes terapéuticos para el control del dolor postoperatorio. |
PMID | 8084247
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Female
- Hemodynamics
(drug effects)
- Humans
- Male
- Middle Aged
- Nalbuphine
(administration & dosage)
- Pain, Postoperative
(drug therapy)
- Prospective Studies
|