[The virological safety and bacterial sterility of a method for fractionating blood plasma proteins with rivanol].

Abstract

The bacterial and virological safety of the method of rivanol fractionation of blood plasma proteins has been evaluated in experiments with samples of donor blood plasma mixed with the suspension of viruses and Escherichia coli used as models. The bacteriostatic action of rivanol and the elimination of bacteriophage and influenza virus from the end product at the stages of rivanol precipitation and adsorption on carbon have been established.

• Authors: N A Zhurina, T L Shatskaia, N V Katushkina
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1993 Jan-Feb Issue 1 Pg. 45-8 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Izuchenie virusologicheskoĭ bezopasnosti i bakterial'noĭ steril'nosti metoda fraktsionirovaniia belkov plazmy krovi s rivanolom.
• PMID: 8067072 (Publication Type: Journal Article)

Chemical References

• Blood Proteins
• Ethacridine

Topics

• Bacteria (drug effects)
• Bacteriophages (drug effects)
• Blood Proteins (isolation & purification)
• Escherichia coli (drug effects)
• Ethacridine (pharmacology)
• Humans
• Influenza A virus (drug effects)
• Safety
• Sterilization (methods)
• Time Factors
• Viruses (drug effects)