Abstract |
Fifty-two consecutive infants who received intravenous indomethacin, 0.2 mg/kg, were reviewed to determine factors associated with the occurrence of oliguria. Serum creatinine and concentration prior to indomethacin did not predict the occurrence of oliguria. A mean urine output of less than 4.5 mL/kg/hr prior to the administration of indomethacin was the only factor that we determined to be associated with a significant risk of oliguria. Two infants developed symptomatic oliguria and both had a pre- indomethacin urine output less than 1.5 mL/kg/hr.
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Authors | K J Barrington, M Fox |
Journal | American journal of perinatology
(Am J Perinatol)
Vol. 11
Issue 3
Pg. 220-2
(May 1994)
ISSN: 0735-1631 [Print] United States |
PMID | 8048989
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Creatinine
(blood)
- Ductus Arteriosus, Patent
(drug therapy)
- Humans
- Indomethacin
(adverse effects)
- Infant, Newborn
- Infant, Premature, Diseases
(drug therapy)
- Oliguria
(chemically induced)
- Prognosis
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