[Thyroid function in brain concussion].

RIA was used to study the quantitative content in the blood serum of thyrotropic (TTH), thyroid (total thyroxine (T4), free thyroxine, triiodothyronine (T3) hormones and thyroxine-binding capacity of blood plasma proteins in 30 patients with brain concussion from the first to the 12th day of disease. The patients' hormonal profile was characterized by normal characteristics of TTH, depression of the transport organic phase of thyroid metabolism with a decrease of the T4 concentration, a reduction of the thyroxine-binding capacity of plasma protein, and simultaneous activation of the peripheral stage of iodine metabolism with excess accumulation in the blood of active hormones--free thyroxine and T3. The data obtained deepen our understanding of the pathogenesis of craniocerebral injury (CCI). The neuroendocrine syndrome identified is specific for mild CCI. It can be used as a differential diagnostic criterion for expert medical evaluation purposes.
AuthorsA A Shutov, A A Chudinov
JournalZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 93 Issue 2 Pg. 39-42 ( 1993) ISSN: 1997-7298 [Print] RUSSIA
Vernacular TitleFunktsional'noe sostoianie shchitovidnoĭ zhelezy pri sotriasenii golovnogo mozga.
PMID8048305 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Thyroid Hormones
  • Adolescent
  • Adult
  • Brain Concussion (blood, diagnosis, physiopathology)
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radioimmunoassay
  • Thyroid Gland (physiopathology)
  • Thyroid Hormones (blood)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: