Abstract | PURPOSE: Intraocular infection caused by Candida species can have devastating visual consequences. With the emergence of Candida as a major nosocomial pathogen, the authors investigated the prevalence of ocular lesions in patients with candidemia and evaluated risk factors for eye involvement. METHODS: This study is a prospective, multicentered, observational design. One hundred eighteen patients with candidemia were evaluated by the infectious disease service and received indirect ophthalmologic examination within 72 hours of a reported positive blood culture. Ocular findings were classified on the basis of objective, pre-determined criteria. Candida chorioretinitis was defined as the presence of focal, white, infiltrative chorioretinal lesions without vitreal involvement. Candida endophthalmitis was defined as chorioretinitis with extension into the vitreous or intravitreal "fluff balls." RESULTS: CONCLUSION: Patients with candidemia who have the risk factors noted above warrant formal ophthalmologic examination.
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Authors | S P Donahue, C M Greven, J J Zuravleff, A W Eller, M H Nguyen, J E Peacock Jr, M W Wagener, V L Yu |
Journal | Ophthalmology
(Ophthalmology)
Vol. 101
Issue 7
Pg. 1302-9
(Jul 1994)
ISSN: 0161-6420 [Print] United States |
PMID | 8035995
(Publication Type: Journal Article, Multicenter Study)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antifungal Agents
(therapeutic use)
- Candidiasis
(microbiology)
- Chorioretinitis
(drug therapy, microbiology, pathology)
- Eye Infections, Fungal
(microbiology)
- Female
- Fundus Oculi
- Fungemia
(complications)
- Humans
- Male
- Middle Aged
- Prevalence
- Prospective Studies
- Retina
(microbiology, pathology)
- Risk Factors
- Visual Acuity
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