[Transfer of photosensitive epilepsy of genetic origin by selective grafts of brain vesicles in chick embryo].

Abstract

We transferred the avian photosensitive genetic epilepsy to normal chicken by transplanting at least prosencephalic and mesencephalic vesicles from epileptic to normal chick embryos at day 2 of incubation. Chimeras showed typical interictal EEG and developed, under intermittent light stimulation, seizures phenotypically and electrically similar to the epileptic strain seizures.

• Authors: M A Teillet, N Guy, B Schuler, G Le Gal La Salle, C Batini, N Le Douarin, R Naquet
• Journal: Comptes rendus des seances de la Societe de biologie et de ses filiales (C R Seances Soc Biol Fil) Vol. 187 Issue 3 Pg. 384-9 ( 1993) ISSN: 0037-9026 [Print] France
• Vernacular Title: Transfert d'une épilepsie photosensible d'origine génétique par greffes sélectives de vésicules cérébrales chez l'embryon de Poulet.
• PMID: 8019914 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Chick Embryo
• Epilepsy (genetics)
• Light
• Mesencephalon (transplantation)
• Prosencephalon (transplantation)
• Rhombencephalon (transplantation)
• Transplantation Chimera