[A case of the successful use of regional thrombolytic therapy in acute ischemic stroke].

Abstract

The paper reports a case of a positive response to fibrinolytic therapy with complete lysis of the thrombus in the left internal carotid artery (ICA) and significant reduction of the baseline neurological deficiency. The vessel later on underwent rethrombosis, but the patient's condition remained stable. Acute ICA occlusion, recovery of the major circulation and subsequent rethrombosis were confirmed angiographically. The intraarterial thrombolytic therapy started 12 hours after the apoplexy. The relief of the major artery occlusion in an acute period of cerebral ischemia prevented the development of infarction and promoted adequate collateral circulation due to which subsequent rethrombosis appeared asymptomatic. It is suggested that intraarterial fibrinolytic agents may be effective as well at later postapoplectic periods (after 6 hours and later).

• Authors: K Iu Polosin, E M Burtsev
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 94 Issue 1 Pg. 85-7 ( 1994) ISSN: 1997-7298 [Print] Russia (Federation)
• Vernacular Title: Sluchaĭ uspeshnogo primeneniia regional'noĭ tromboliticheskoĭ terapii pri ostrom ishemicheskom insul'te.
• PMID: 8009942 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Streptokinase

Topics

• Acute Disease
• Adult
• Carotid Artery Thrombosis (complications, diagnostic imaging, drug therapy)
• Carotid Artery, Internal (diagnostic imaging)
• Drug Therapy, Combination
• Hemiplegia (diagnostic imaging, drug therapy, etiology)
• Humans
• Ischemic Attack, Transient (diagnostic imaging, drug therapy, etiology)
• Male
• Radiography
• Recurrence
• Remission Induction
• Streptokinase (therapeutic use)
• Thrombolytic Therapy (methods)