Treatment of stiff-man syndrome with intravenous immune globulin.

Abstract

OBJECTIVE:

To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff-man syndrome (SMS).

METHODS:

An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids.

RESULTS:

All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function.

CONCLUSION:

IVIG may be useful for the treatment of SMS.

• Authors: E W Karlson, L Sudarsky, E Ruderman, S Pierson, M Scott, S M Helfgott
• Journal: Arthritis and rheumatism (Arthritis Rheum) Vol. 37 Issue 6 Pg. 915-8 (Jun 1994) ISSN: 0004-3591 [Print] United States
• PMID: 8003064 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adult
• Aged
• Female
• Humans
• Immunoglobulins, Intravenous (administration & dosage)
• Middle Aged
• Stiff-Person Syndrome (complications, therapy)