One-week therapy with oral terbinafine in cases of tinea cruris/corporis.

Abstract

The use of oral terbinafine in the treatment of superficial dermatophyte infections has been extensively studied, using different treatment regimens. To evaluate the efficacy of short-term therapy with oral terbinafine in cases of tinea cruris/corporis, 22 patients (21 male and one female) with mycologically proven tinea cruris/corporis, were included in the present study. Each patient received one tablet of terbinafine 250 mg daily for 1 week. Patients were followed-up for 6 weeks after completion of treatment. Clinical and mycological assessments were performed at the end of treatment, and at the end of the follow-up period. The mean sum of scores of signs and symptoms in all patients decreased significantly from 12.36 before treatment to 0 at the end of the follow-up period, and mycological investigations were negative in all patients at the end of the follow-up period. Our results show that 1-week therapy with oral terbinafine is highly effective in the treatment of tinea cruris/corporis.

• Authors: A Farag, M Taha, S Halim
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 131 Issue 5 Pg. 684-6 (Nov 1994) ISSN: 0007-0963 [Print] England
• PMID: 7999601 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Antifungal Agents
• Naphthalenes
• Terbinafine

Topics

• Administration, Oral
• Adult
• Antifungal Agents (administration & dosage)
• Drug Administration Schedule
• Female
• Follow-Up Studies
• Humans
• Male
• Naphthalenes (administration & dosage)
• Terbinafine
• Tinea (drug therapy)