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Normal oxygen tension restored in the ischemic rat liver model by PEG-hemoglobin.

Abstract
Cell damage initiated during ischemia, as a result of oxygen depletion, continues during reperfusion, and recovery is dependent on the length of the ischemic period. This study investigates the effect of polyethylene glycol-modified hemoglobin (PEG-Hb) on recovery of tissue oxygen tension after induced ischemia.
AuthorsR Linberg, M Johnson, K Nho, C Gilbert, R Shorr
JournalArtificial cells, blood substitutes, and immobilization biotechnology (Artif Cells Blood Substit Immobil Biotechnol) Vol. 22 Issue 3 Pg. 805-12 ( 1994) ISSN: 1073-1199 [Print] England
PMID7994403 (Publication Type: Journal Article)
Chemical References
  • Blood Substitutes
  • Hemoglobins
  • Polyethylene Glycols
  • Aspartate Aminotransferases
  • Alanine Transaminase
  • Oxygen
Topics
  • Alanine Transaminase (metabolism)
  • Animals
  • Aspartate Aminotransferases (metabolism)
  • Blood Substitutes (metabolism, pharmacology)
  • Cattle
  • Hemoglobins (metabolism, pharmacology)
  • Ischemia (metabolism, therapy)
  • Liver (blood supply, metabolism)
  • Oxygen (metabolism)
  • Polyethylene Glycols (pharmacology)
  • Rats
  • Rats, Sprague-Dawley
  • Time Factors

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