HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[An evaluation of the effectiveness of laboratory diagnostic methods for brucellosis].

Abstract
The diagnostic value of bacteriological and serological methods for the laboratory diagnosis of brucellosis was studied. In the analysis of milk and cheese specimens Brucella cultures were isolated and differentiated as B.melitensis, biovar I, and B.abortus, biovar 4. In 25.6% of cases B.melitensis culture, biovar 1, was isolated from the blood of persons suspected for brucellosis. The isolation of B.melitensis culture from milk showed that this infective agent migrated from small animals to cattle, which was indicative of a high risk of human infection in the state of Zacatecas, Mexico. The comparative evaluation of serological diagnostic methods (the agglutination test in test tubes, Huddleson's slide test, the acidic rose bengal test and the 2-mercaptoethanol test) showed high sensitivity of rapid tests (Huddleson's test and the rose bengal test in 93.7% and 87.9% of cases respectively). The 2-mercaptoethanol test which gave positive results in 63.8% of cases provided additional information characterizing the course of infections process.
AuthorsB Gandara, M M Zheludkov, M I Chernysheva
JournalZhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1994 Jul-Aug Issue 4 Pg. 55-8 ISSN: 0372-9311 [Print] Russia (Federation)
Vernacular TitleOtsenka éffektivnosti metodov laboratornoĭ diagnostiki brutselleza.
PMID7992538 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Antibodies, Bacterial
  • Immunoglobulin M
Topics
  • Animals
  • Antibodies, Bacterial (blood)
  • Antibody Specificity
  • Brucella abortus (classification, immunology, isolation & purification)
  • Brucella melitensis (classification, immunology, isolation & purification)
  • Brucellosis (diagnosis, microbiology, transmission)
  • Evaluation Studies as Topic
  • Humans
  • Immunoglobulin M (blood)
  • Immunologic Tests (methods)
  • Mexico
  • Milk (microbiology)
  • Sensitivity and Specificity
  • Serotyping

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: