Abstract |
We report a rare case of pulmonary blastoma. This 59-year-old woman has been apparently well with recurrent and metastatic tumors in her left lung for 9 years after the initial operation. On May 28, 1984, she underwent a thoracotomy of left upper lobectomy and lymph nodes dissection. The histologic diagnosis of resected specimen was pulmonary blastoma. In August 1986 (27 months after the initial surgery), chest X-ray revealed some nodules in the lungs. Then, the patient had two thoracotomies for the excision of 4 tumors and one chest wall resection of the tumor. In addition, she received systemic chemotherapy 28 times, directly intrapulmonary drug injection 3 times and radiation therapy once for recurrent and metastatic disease. Following some cycles of our combination chemotherapy consisting of cis-platinum and vindesine, some lesions had decreased in size and others previously seen on chest X-ray were no longer evident. She achieved an objective response with receiving two- drug chemotherapy. Our observation suggest that this intensive combination chemotherapy is effective in recurrent and metastatic disease of pulmonary blastoma as a surgical adjuvant.
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Authors | I Suzuki, K Oho, S Nakayama, K Tamura, M Tsuboi, H Okitsu |
Journal | [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
(Nihon Kyobu Geka Gakkai Zasshi)
Vol. 42
Issue 8
Pg. 1208-13
(Aug 1994)
ISSN: 0369-4739 [Print] Japan |
PMID | 7963837
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Chemotherapy, Adjuvant
- Combined Modality Therapy
- Female
- Humans
- Lung Neoplasms
(pathology, therapy)
- Lymph Node Excision
- Middle Aged
- Neoplasm Recurrence, Local
- Pneumonectomy
- Prognosis
- Pulmonary Blastoma
(secondary, therapy)
- Radiotherapy, Adjuvant
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