Chronic hepatitis C complicated by Coombs-negative hemolytic anemia during interferon treatment.

Abstract

Autoimmune hemolytic anemia is an autoimmune diseases which is reported to be caused by interferon treatment. A 33-year-old male with chronic hepatitis C developed Coombs-negative hemolytic anemia, probably due to administration of interferon-alpha 2b. This is, to our knowledge, the first report of chronic hepatitis C complicated by Coombs-negative hemolytic anemia during interferon treatment.

• Authors: N Hirashima, M Mizokami, E Orito, M Yamauchi, M Narita, M Mizuno, Y Tokuda, T Nakano, M Kato, T Matsumoto
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 33 Issue 5 Pg. 300-2 (May 1994) ISSN: 0918-2918 [Print] Japan
• PMID: 7949634 (Publication Type: Case Reports, Journal Article)

Chemical References

• Interferon alpha-2
• Interferon-alpha
• Recombinant Proteins

Topics

• Acute Kidney Injury (diagnosis, etiology)
• Adult
• Anemia, Hemolytic, Autoimmune (complications, diagnosis, etiology)
• Coombs Test
• Hepatitis C (complications, pathology, therapy)
• Hepatitis, Chronic (complications, pathology, therapy)
• Humans
• Interferon alpha-2
• Interferon-alpha (adverse effects)
• Male
• Recombinant Proteins