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Carcinoid heart disease: early failure of an allograft valve replacement.

Abstract
A woman who had carcinoid syndrome and carcinoid heart disease underwent tricuspid and pulmonary valve replacements with a xenograft and a cryopreserved allograft, respectively. Within 3 months of the operation severe pulmonary regurgitation and pulmonary hypertension refractory to medical therapy developed. Autopsy found the biomechanical tricuspid valve to be free of disease but the allograft in the pulmonary position was involved by carcinoid heart disease in a fashion similar to the excised native pulmonary valve.
AuthorsS K Ohri, J B Schofield, H Hodgson, C M Oakley, B E Keogh
JournalThe Annals of thoracic surgery (Ann Thorac Surg) Vol. 58 Issue 4 Pg. 1161-3 (Oct 1994) ISSN: 0003-4975 [Print] Netherlands
PMID7944771 (Publication Type: Case Reports, Journal Article, Review)
Topics
  • Carcinoid Heart Disease (surgery)
  • Fatal Outcome
  • Female
  • Heart Valve Prosthesis
  • Humans
  • Middle Aged
  • Prosthesis Failure
  • Pulmonary Valve
  • Tricuspid Valve

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