In 1992, the Swiss Public Health Office introduced an expanded
tuberculosis screening program for refugees. In addition to routine chest X-rays, it includes
tuberculosis skin testing and prophylactic treatment with
isoniazid of skin test positive individuals. In addition, a
vaccine program has been established which, besides routine
hepatitis B vaccination of anti-HBc negative individuals, includes vaccination of all refugees against
tetanus,
diphtheria,
polio,
measles,
mumps and
rubella. The two-year experience of this expanded program is reported from Canton Basel-Stadt, Switzerland. During the two-year period (1992 to 1993), 289 adults and 53 children were screened. In 3.1% (n = 9) of 289 refugees who were examined by X-ray, smear positive
tuberculosis was found. These 9 cases contributed 12% of all
tuberculosis cases identified in Canton Basel-Stadt during the observation period. In 4.4% of all refugees prophylactic treatment with
isoniazid was initiated, but 7 of the 15 cases (46.6%) did not complete the prophylaxis. In contrast, compliance with the
vaccine program was better and complete vaccination was achieved in 90% of all refugees. The prevalence of anti-HBc
antibodies was 28.7% and highest among refugees from Turkey (48.6%) and Africa (34.2%). X-ray screening for
tuberculosis in high risk populations such as refugees is effective. However, compliance with 6 months' prophylactic treatment with
isoniazid for skin test positives was only moderate.