Displacement of the normal pituitary gland by sellar and juxtasellar tumours: surgical-MRI correlation and use in differential diagnosis.

We compared the position of the normal pituitary gland as estimated by gadolinium (Gd)-DTPA-enhanced MRI, with its position at surgery in 40 patients with intra- and juxtasellar tumours: 22 pituitary adenomas, 4 craniopharyngiomas, 7 meningiomas, 2 germinomas, and 5 Rathke cleft cysts. In 37 of these, the normal gland showed more intense contrast enhancement than the adjacent tumour, from which it could be differentiated by Gd-DTPA-enhanced MRI, especially in the sagittal plane. The direction of displacement of the normal pituitary gland correlated well with tumour type, so that its position proved helpful in the differential diagnosis. The normal gland was typically displaced superiorly by pituitary adenomas, inferiorly by craniopharyngiomas, and anteriorly by germinomas. It showed variable displacement by Rathke cleft cysts, and was not usually displaced by meningiomas.
AuthorsM Sumida, T Uozumi, M Yamanaka, K Mukada, K Arita, K Kurisu, H Satoh, F Ikawa
JournalNeuroradiology (Neuroradiology) Vol. 36 Issue 5 Pg. 372-5 (Jul 1994) ISSN: 0028-3940 [Print] GERMANY
PMID7936178 (Publication Type: Journal Article)
  • Adenoma (diagnosis, surgery)
  • Brain Neoplasms (diagnosis, surgery)
  • Craniopharyngioma (diagnosis, surgery)
  • Diagnosis, Differential
  • Germinoma (diagnosis, surgery)
  • Humans
  • Magnetic Resonance Imaging
  • Meningioma (diagnosis, surgery)
  • Pituitary Gland (pathology, surgery)
  • Pituitary Neoplasms (diagnosis, surgery)
  • Sella Turcica

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