[The efficacy of polyoxydine and mafusol in the combined treatment of acute surgical blood loss].

Abstract

The authors have studied the efficiency of new blood substitutes (polyoxidin and mafusol) in complex infusion-transfusion therapy in operations on lungs. During surgical interventions these medications were administered in doses of 717.0 +/- 30.0 ml and 914.0 +/- 74.0 correspondingly, and one day after the operation--400 ml each. Operational blood losses were 1.25 +/- 0.9 l. It was found out that polyoxidin and mafusol have executed positive influence upon various factors of pathophysiological mechanisms, and thus were effective in complex treatment of blood losses or shock states.

• Authors: V G Artemov, G V Butko
• Journal: Voenno-meditsinskii zhurnal (Voen Med Zh) Issue 12 Pg. 29-32, 80 (Dec 1994) ISSN: 0026-9050 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' polioksidina i mafusola v kompleksnom lechenii ostroĭ operatsionnoĭ krovopoteri.
• PMID: 7900315 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Blood Substitutes
• Formates
• Hemostatics
• polyoxydine
• formic acid
• Polyethylene Glycols

Topics

• Acid-Base Equilibrium (drug effects)
• Acute Disease
• Blood Loss, Surgical (physiopathology)
• Blood Substitutes (pharmacology, therapeutic use)
• Drug Evaluation
• Formates (pharmacology, therapeutic use)
• Hemodynamics (drug effects)
• Hemostatics (pharmacology, therapeutic use)
• Humans
• Lung (surgery)
• Polyethylene Glycols