[Experimental and clinical studies of the effect of pectin on the causative agents of acute intestinal infections].

Abstract

The effect of alimentary pectin obtained from different raw materials (apple, tomato, cotton-wool) on the causative agents of infectious diarrheal diseases, belonging to the genera Shigella, Salmonella, Klebsiella, Enterobacter, Proteus and Citrobacter, was studied under experimental conditions and in clinical observations. The study revealed that pectin, irrespective of raw material used for its production, produced an inhibiting effect on these microorganisms. This effect was most pronounced, both under experimental and clinical conditions, when 5% pectin solution was used. A rapid suppress of diarrhea and other manifestations of the infectious syndrome was observed in patients. The patients treated with pectin stayed in the hospital, on the average, 2-3 days less than the control group of patients treated with antibiotics and other chemotherapeutic preparations.

• Authors: E G Potievskiĭ, Sh Sh Shavakhabov, V M Bondarenko, Z D Ashubaeva
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1994 Aug-Sep Vol. Suppl 1 Pg. 106-9 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Eksperimental'noe i klinicheskoe izuchenie vliianiia pektina na vozbuditeleĭ ostrykh kishechnykh infektsiĭ.
• PMID: 7856335 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Pectins

Topics

• Acute Disease
• Adolescent
• Adult
• Bacteria (drug effects, isolation & purification)
• Bacterial Infections (drug therapy, microbiology)
• Dose-Response Relationship, Drug
• Drug Evaluation
• Female
• Humans
• Intestinal Diseases (drug therapy, microbiology)
• Male
• Microbial Sensitivity Tests
• Pectins (pharmacology, therapeutic use)
• Time Factors