[Itraconazole in the treatment of ophthalmomycoses].

Abstract

The method and results of the use of itrakonazol, a new antifungal agent of the imidazol class, in the treatment of fungal diseases of the eye are described. The clinical trials involved 50 patients with various clinical forms of ophthalmomycosis: 27 patients with fungal affection of the cornea, 3 patients with fungal endophthalmitis, 8 patients with fungal canaliculitis, 3 patients with fungal blepharitis and 9 patients with fungal conjunctivitis. The clinical trials showed that itraconazole had a sufficiently high antifungal activity in the treatment of the ophthalmomycoses. The drug is low toxic and well tolerated.

• Authors: Iu F Maĭchuk, U V Diadina
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 39 Issue 7 Pg. 54-6 (Jul 1994) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Itrakonazol v lechenii oftal'momikozov.
• PMID: 7840712 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Itraconazole

Topics

• Blepharitis (drug therapy)
• Conjunctivitis (drug therapy)
• Corneal Diseases (drug therapy)
• Endophthalmitis (drug therapy)
• Eye Infections, Fungal (drug therapy)
• Humans
• Itraconazole (adverse effects, therapeutic use)