Abstract |
Atypical mycobacteria, which are common opportunistic pathogens in patients with AIDS, have not been previously implicated in the pathogenesis of paranasal sinus infections; we describe two such patients. Clinical and radiographic evidence of bilateral maxillary and ethmoid sinusitis was observed for one patient; his infection proved resistant to therapy with conventional antimicrobials and decongestants. Endoscopic ethmoid sinus biopsy yielded a specimen containing acid-fast bacilli (AFB) that were later identified as Mycobacterium kansasii. Antimycobacterial therapy had not resulted in amelioration of the sinusitis > 2 months later, at which time he died of cerebral toxoplasmosis. The second patient presented with a tender right frontotemporal soft-tissue mass; a computed tomogram disclosed that it extended through the frontal bone to the frontal sinus. Inflamed tissue debrided from the sinus contained AFB; cultures first yielded M. kansasii and later Mycobacterium avium complex. Bacteremia due to both organisms was also demonstrated. Infection progressed despite therapy.
|
Authors | M T Naguib, J M Byers, L N Slater |
Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
(Clin Infect Dis)
Vol. 19
Issue 4
Pg. 789-91
(Oct 1994)
ISSN: 1058-4838 [Print] United States |
PMID | 7803653
(Publication Type: Case Reports, Journal Article)
|
Topics |
- AIDS-Related Opportunistic Infections
(diagnosis, drug therapy, microbiology)
- Adult
- Humans
- Male
- Mycobacterium Infections, Nontuberculous
(diagnosis, drug therapy)
- Nontuberculous Mycobacteria
(isolation & purification)
- Paranasal Sinus Diseases
(diagnosis, drug therapy, microbiology)
|