Abstract |
The presence and dynamic change of autoantibody against ADP/ATP carrier in patients with dilated cardiomyopathy (DCM) was studied by using indirect micro-solid-phase radioimmunoassay. A significant antibody titre was present in 16 of 48 DCM patients and most of them were in early stage of the disease. The titre of anti- ADP/ATP carrier antibody in DCM patients decreased gradually in a follow-up period of three months. The titre of this antibody in the serum from patients with coronary and rheumatic heart disease were within normal limits. Anti- ADP/ATP carrier antibody may play an important role in the pathogenesis, diagnosis and treatment of DCM.
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Authors | W Zhang, Z Liu, D Yang |
Journal | Zhonghua nei ke za zhi
(Zhonghua Nei Ke Za Zhi)
Vol. 34
Issue 2
Pg. 95-7
(Feb 1995)
ISSN: 0578-1426 [Print] China |
PMID | 7796665
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Autoantibodies
- CD8 Antigens
- Mitochondrial ADP, ATP Translocases
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Topics |
- Adult
- Aged
- Autoantibodies
(blood)
- CD8 Antigens
(immunology)
- Cardiomyopathy, Dilated
(diagnosis, immunology)
- Female
- Humans
- Lymphocyte Count
- Male
- Middle Aged
- Mitochondrial ADP, ATP Translocases
(immunology)
- Radioimmunoassay
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