[Vulvar involvement in Crohn disease].

Abstract

INTRODUCTION:

There are many skin manifestations of Crohn's disease including specific lesions occurring late after digestive signs. These manifestations are also termed metastatic and are rarely located on the vulva.

CASE REPORT:

We observed a metastatic localization in the vulva of Crohn's disease in a 34-year-old woman with predominantly rectosigmoid disease. The right labia major was greatly enlarged with oedema involving the inguinal cural area. Pustulization and erosive lesions were seen. The course of these lesions was independent of the colonic disease and responded temporarily only to a triple drug combination of metronidazol, prednisolone and minocyclin.

CONCLUSION:

This case emphasizes the frequency of colonic or rectal manifestations associated with vulval involvement in Crohn's disease. The metastatic lesions follow a course independent of the digestive disease raising therapeutic problems in this localization.

• Authors: S Doassans, H Osman, J M Joujoux, B Guillot
• Journal: Annales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 121 Issue 10 Pg. 724-6 ( 1994) ISSN: 0151-9638 [Print] France
• Vernacular Title: Atteinte vulvaire au cours d'une maladie de Crohn.
• PMID: 7793764 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Metronidazole

Topics

• Adult
• Crohn Disease (complications)
• Edema (drug therapy, etiology, pathology)
• Female
• Humans
• Metronidazole (therapeutic use)
• Vulvar Diseases (drug therapy, etiology, pathology)