Inhaled nitric oxide and extracorporeal membrane oxygenation in persistent pulmonary hypertension of the newborn.

Abstract

Persistent pulmonary hypertension of the newborn (PPHN) may occasionally require an invasive treatment with extracorporeal membrane oxygenation (ECMO). Inhaled nitric oxide (NO) has recently been introduced as a selective pulmonary vasodilator for treatment of PPHN. We describe a case of PPHN in which neither inhaled NO nor ECMO was effective in reversing pulmonary hypertension. The clinical course of the patient suggested a potential role of NO inhalation in predicting the outcome of ECMO treatment for PPHN.

• Authors: M Takata, K Miyasaka, H Sakai, H Fujiwara, Y Ito, T Kawano
• Journal: Acta paediatrica Japonica : Overseas edition (Acta Paediatr Jpn) Vol. 37 Issue 2 Pg. 171-3 (Apr 1995) ISSN: 0374-5600 [Print] Australia
• PMID: 7793249 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vasodilator Agents
• Nitric Oxide

Topics

• Administration, Inhalation
• Extracorporeal Membrane Oxygenation
• Humans
• Infant, Newborn
• Male
• Nitric Oxide (administration & dosage)
• Persistent Fetal Circulation Syndrome (therapy)
• Treatment Failure
• Vasodilator Agents (therapeutic use)