Successful treatment of epidermolysis bullosa acquisita using intravenous immunoglobulins.

Abstract

We report a 55-year-old man with severe inflammatory epidermolysis bullosa acquisita. The skin lesions did not respond to various immunosuppressive treatments. The combined administration of prednisone, azathioprine, dapsone and colchicine resulted only in a transient and incomplete resolution of the lesions. The bullae and increased skin fragility were successfully controlled by the addition of high-dose intravenous immunoglobulin therapy.

• Authors: C Mohr, C Sunderkötter, A Hildebrand, K Biel, A Rütter, G H Rütter, T A Luger, G Kolde
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 132 Issue 5 Pg. 824-6 (May 1995) ISSN: 0007-0963 [Print] England
• PMID: 7772494 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous
• Dapsone
• Azathioprine
• Colchicine
• Prednisone

Topics

• Azathioprine (therapeutic use)
• Colchicine (therapeutic use)
• Dapsone (therapeutic use)
• Drug Therapy, Combination
• Epidermolysis Bullosa Acquisita (therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Male
• Middle Aged
• Prednisone (therapeutic use)