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Low-dose droperidol reduces postoperative vomiting in paediatric day surgery.

Abstract
In a prospective, randomized, blind study, we assessed the effectiveness of droperidol 20 micrograms kg-1 i.v., given at induction of anaesthesia, in preventing postoperative vomiting in paediatric day-case patients. We studied 270 children, aged 1-15 yr, undergoing body surface surgery. There was a significant reduction in the incidence of vomiting in the recovery room (1.4% vs 9.2%, P < 0.005) and in the day ward (9.4% vs 18.3%, P < 0.05) in patients receiving droperidol. There was no significant difference on the journey home (9.5% vs 17.83%, ns) or at home (16.7% vs 10.3%, ns). There was also a reduction in the severity of vomiting in the droperidol group. There were no adverse side effects.
AuthorsD V Lunn, G R Lauder, A R Williams, R M Pickering, P J McQuillian
JournalBritish journal of anaesthesia (Br J Anaesth) Vol. 74 Issue 5 Pg. 509-11 (May 1995) ISSN: 0007-0912 [Print] England
PMID7772422 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Droperidol
Topics
  • Adolescent
  • Ambulatory Surgical Procedures
  • Child
  • Child, Preschool
  • Droperidol (therapeutic use)
  • Female
  • Humans
  • Infant
  • Male
  • Postoperative Complications (prevention & control)
  • Prospective Studies
  • Time Factors
  • Treatment Outcome
  • Vomiting (prevention & control)

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