Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan.

Abstract

The efficacy of Cymelarsan, administered by intramuscular (i/m) injection in the treatment of chronic cases of camel trypanosomosis due to Trypanosoma evansi, was tested under controlled laboratory conditions. It was confirmed that Cymelarsan is a safe drug for use in dromedary camels when administered i/m at dose rates of 0.25 or 0.50 mg/kg body weight. During the 90 days post-treatment no relapses occurred at either dose rate. Hence, the drug was found to be fully effective against the chronic form of the natural disease. A dose of 0.25 mg/kg body weight of Cymelarsan given i/m is recommended.

• Authors: M M Musa, A M Abdoon, B T Nasir, Y I Salim, A Y Abdel-Rahman, A M Shommein
• Journal: Revue d'elevage et de medecine veterinaire des pays tropicaux (Rev Elev Med Vet Pays Trop) Vol. 47 Issue 4 Pg. 397-400 ( 1994) ISSN: 0035-1865 [Print] France
• PMID: 7770663 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Arsenicals
• Trypanocidal Agents
• melaminylthioarsenate

Topics

• Animals
• Arsenicals (therapeutic use)
• Camelus (parasitology)
• Sudan
• Trypanocidal Agents (therapeutic use)
• Trypanosomiasis, African (drug therapy, veterinary)