Abstract |
Add-on therapy with flunitrazepam (FNZ) was performed in 5 children with marked sleep disturbance and intractable seizures. Correction of the sleep disturbance was attained immediately after the start of FNZ administration in all patients. Furthermore, a significant decrease in the seizure frequency (3 patients) and improved quality of life (4 patients) were concomitantly observed. There was no adverse effect or interaction with conventional AEDs on long-term use.
|
Authors | T Konishi, K Masuko, Y Naganuma, K Hongou, S Yagi |
Journal | Brain & development
(Brain Dev)
1995 Jan-Feb
Vol. 17
Issue 1
Pg. 69-72
ISSN: 0387-7604 [Print] Netherlands |
PMID | 7762768
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
|
Topics |
- Child
- Child, Preschool
- Epilepsy
(complications)
- Flunitrazepam
(therapeutic use)
- Humans
- Male
- Sleep Wake Disorders
(drug therapy, etiology)
|