Follow-up of primary Palmaz-Schatz stent placement for atherosclerotic renal artery stenosis.

Abstract

A Palmaz-Schatz stent was successfully placed in 92 stenotic renal arteries (76 patients) for (1) hypertension in 62 (82%), and/or (2) chronic renal failure (serum creatinine > or = 1.5 mg/dl) and preservation of renal function in 39 (51%). Patients were followed to assess clinical and angiographic 6-month outcome. Angiography, performed in 45 of 62 eligible patients (73%) and in 56 of 74 treated arteries (76%), showed restenosis occurring in 14 renal arteries (25%). Serum creatinine improved or remained stable in 78% of patients. In patients with chronic renal failure, improvement or stability was observed in 55%. Blood pressure recordings significantly decreased for the entire cohort (systolic: 168 +/- 25 to 156 +/- 22 mm Hg, p < 0.0001; diastolic: 87 +/- 11 to 81 +/- 11 mm Hg, p < 0.005), and for hypertensive patients with normal creatinine (systolic: 179 +/- 20 to 155 +/- 23 mm Hg, p < 0.0001; diastolic: 92 +/- 9 to 83 +/- 12 mm Hg, p < 0.002). These follow-up data of a prospective, nonrandomized, observational study showed that stent recanalization of atherosclerotic renal artery stenoses was beneficial with regard to renal function and blood pressure response, and had a restenosis incidence of 25%.

• Authors: G Dorros, M Jaff, A Jain, C Dufek, L Mathiak
• Journal: The American journal of cardiology (Am J Cardiol) Vol. 75 Issue 15 Pg. 1051-5 (May 15 1995) ISSN: 0002-9149 [Print] United States
• PMID: 7747688 (Publication Type: Clinical Trial, Journal Article, Multicenter Study)

Chemical References

• Creatinine

Topics

• Aged
• Arteriosclerosis (complications, diagnostic imaging, surgery)
• Blood Pressure
• Cohort Studies
• Creatinine (blood)
• Female
• Follow-Up Studies
• Humans
• Hypertension, Renovascular (etiology, physiopathology)
• Kidney Failure, Chronic (blood, etiology)
• Male
• Middle Aged
• Prospective Studies
• Radiography
• Recurrence
• Renal Artery (diagnostic imaging)
• Renal Artery Obstruction (complications, diagnostic imaging, surgery)
• Stents
• Wisconsin