[The interrelationship of the thyroid and immune statuses of workers with long-term fluorine exposure].

Abstract

Thyroid and immune statuses were studied in workers continuously exposed to fluorine. The examinees with euthyroid condition had immune disorders with an allergic tendency (increased number of B-lymphocytes, immunoglobulins A). In workers with subclinical hypothyrosis (tri-iodothyronine reduced in 51%), the immune alterations were more evident, T-lymphocytes count rose, but their functional activity declined, indicating impaired cooperation of immunocytes as a result of imperfect control under low concentrations of tri-iodothyronine.

• Authors: M I Balabolkin, N D Mikhaĭlets, R N Lobovskaia, N V Chernousova
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 67 Issue 1 Pg. 41-2 ( 1995) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Vzaimosviaz' tireoidnogo i immunnogo statusov u rabochikh pri dlitel'nom vozdeĭstvii ftora.
• PMID: 7709355 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Aluminum

Topics

• Adult
• Aluminum
• Chi-Square Distribution
• Chronic Disease
• Fluoride Poisoning (immunology, physiopathology)
• Humans
• Immune System (drug effects, immunology)
• Male
• Metallurgy
• Middle Aged
• Occupational Diseases (chemically induced, immunology, physiopathology)
• Thyroid Gland (drug effects, physiopathology)