Abstract | BACKGROUND: Friction blisters are a common injury in sports activities and military operations. Blisters can compromise performance, so it is important to devise preventive strategies to reduce these injuries. OBJECTIVE: METHODS: Twenty-three healthy men walked on a treadmill (1.39 m/sec, 1% grade) in a warm environment (28 degrees C, 25% relative humidity) carrying a total mass of 21 +/- 1 kg. For 4 consecutive days before the walk, the subjects' feet were treated with either (1) an antiperspirant (20% aluminum zirconium tetrachlorohydrex glycine concentration plus water) with emollient additives, (2) emollient additives alone (placebo control), or (3) nothing (nontreated). In two separate trials (1 month apart) each participant received the antiperspirant treatment and both control treatments ( emollient [placebo] and no treatment). RESULTS: No differences were seen among treatment conditions for sweat accumulation (p = 0.86), blister incidence (p = 0.36), hot spot incidence (p = 0.83), or blister severity (p = 0.31). Irritant dermatitis was not reported in any of the treatment conditions. CONCLUSION:
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Authors | K Reynolds, A Darrigrand, D Roberts, J Knapik, J Pollard, K Duplantis, B Jones |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 33
Issue 4
Pg. 626-30
(Oct 1995)
ISSN: 0190-9622 [Print] United States |
PMID | 7673497
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Aluminum Compounds
- Astringents
- Chlorides
- Emollients
- Placebos
- Aluminum Chloride
- Zirconium
- Glycine
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Topics |
- Adult
- Aluminum Chloride
- Aluminum Compounds
(therapeutic use)
- Astringents
(therapeutic use)
- Blister
(pathology, prevention & control)
- Chlorides
(therapeutic use)
- Dermatitis, Irritant
(prevention & control)
- Emollients
(therapeutic use)
- Foot
(physiopathology)
- Foot Diseases
(pathology, prevention & control)
- Friction
- Glycine
(therapeutic use)
- Hot Temperature
- Humans
- Male
- Military Personnel
- Placebos
- Skin Temperature
- Sweat
(drug effects)
- Walking
- Zirconium
(therapeutic use)
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