Pachyonychia congenita tarda.

Abstract

Pachyonychia congenita is a distinct hereditary disorder of keratinization, in which dystrophy of all nails is associated with palmoplantar keratoderma and other hyperkeratoses. Recently a late-onset type has been reported. We report a second family with late-onset pachyonychia congenita, showing a remarkable clinical heterogeneity. Furthermore, one patient demonstrated a number of associated hyperkeratoses not previously recognized. Acitretin proved useful in the treatment of this late-onset form of pachyonychia congenita.

• Authors: G P Lucker, P M Steijlen
• Journal: Clinical and experimental dermatology (Clin Exp Dermatol) Vol. 20 Issue 3 Pg. 226-9 (May 1995) ISSN: 0307-6938 [Print] England
• PMID: 7671418 (Publication Type: Case Reports, Journal Article)

Topics

• Family
• Humans
• Keratoderma, Palmoplantar (pathology)
• Male
• Middle Aged
• Nail Diseases (pathology)
• Syndrome