Abstract |
The Australian freshwater mussel Alathyria condola accumulated high levels of paralytic shellfish poisoning (PSP) toxins when fed the neurotoxic cyanobacterium Anabaena circinalis, shown recently to contain high concentrations of C-toxins and gonyautoxins. Significant accumulation (>80 mu g/100 g of mussel flesh) was detected following 2-3 exposure to water containing 2 x 105 cells/ml A. circinalis. Only trace accumulation of PSP toxins was demonstrated over long-term (5 week) exposure at low concentration (c. 104 cells/ml). The relative abundance of C-toxins, gonyautoxins and saxitoxins in mussels generally matched the toxin profiles of the dietary A. circinalis, although there were differences in the GTX2/3 and C1/2 ratios with time, and an increase in abundance of decarbamoylgonyautoxins. Analysis of mussel tissues after 7 days, exposure to A. circinalis revealed that 96% of the toxins were accumulated in the viscera. As in marine waters, the bioaccumulation of PSP toxins in freshwater mussels may pose a health risk to humans and animals, especially in areas where seasonally decreasing water levels expose mussel beds to surface scums of toxic cyanobacteria.
|
Authors | A P Negri, G J Jones |
Journal | Toxicon : official journal of the International Society on Toxinology
(Toxicon)
Vol. 33
Issue 5
Pg. 667-78
(May 1995)
ISSN: 0041-0101 [Print] England |
PMID | 7660371
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Anabaena
(metabolism)
- Animals
- Biological Assay
- Bivalvia
(metabolism, microbiology)
- Chromatography, High Pressure Liquid
- Mice
- Saxitoxin
(analysis, toxicity)
|