Abstract |
One hundred seventy-seven women aged 41 +/- 8 (mean +/- SD) years, referred for evaluation of excessive uterine bleeding, were enrolled in an open-label randomized trial to evaluate the efficacy of local anesthesia before hysteroscopy in an outpatient population. The patients underwent hysteroscopy and endometrial biopsy with paracervical block by 10 mL of 1% mepivacaine hydrochloride solution (n = 87) or no local anesthesia (n = 90) and assessed lower abdominal and pelvic pain according to a 10-point linear analog scale. The mean +/- SD pain score was 4.5 +/- 2.0 at hysteroscopy and 5.2 +/- 2.1 at endometrial biopsy in the 87 subjects given a paracervical block versus 4.9 +/- 2.2 and 5.7 +/- 2.4 in the 90 women not given local anesthesia, without statistically significant differences. Paracervical anesthesia for routine outpatient hysteroscopy in premenopausal women may be superfluous.
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Authors | P Vercellini, A Colombo, F Mauro, S Oldani, T Bramante, P G Crosignani |
Journal | Fertility and sterility
(Fertil Steril)
Vol. 62
Issue 5
Pg. 1083-5
(Nov 1994)
ISSN: 0015-0282 [Print] United States |
PMID | 7646610
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Topics |
- Adult
- Analgesia
- Anesthesia
- Biopsy
- Cervix Uteri
- Endometrium
(pathology)
- Female
- Humans
- Hysteroscopy
- Middle Aged
- Pain
- Uterine Hemorrhage
(pathology)
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