A trial with fluocinonide in recalcitrant dermatoses.

Abstract

The effectiveness and safety of fluocinonide 0.05% in a cream base (FAPG cream: fatty acid propylene glycol) were evaluated in 105 patients with recalcitrant corticosteroid-responsive dermatoses that had failed to respond adequately to at least two weeks' previous treatment with one of 21 other topical corticosteroid preparations. At the end of the three weeks, 66 (71.0%) of the 93 patients who qualified for analysis showed excellent to moderate improvement with fluocinonide. Side effects were rare and of a minor nature. The general effectiveness of fluocinonide is indicated in this single-blind trail in which excellent or moderate results predominated in 8 of the 12 different diagnosis.

• Authors: R S Medansky, R M Handler, W Cook, C B Willoughby, M J Fellner
• Journal: International journal of dermatology (Int J Dermatol) 1979 Jan-Feb Vol. 18 Issue 1 Pg. 83-8 ISSN: 0011-9059 [Print] England
• PMID: 761964 (Publication Type: Journal Article)

Chemical References

• Ointments
• Fluocinolone Acetonide
• Fluocinonide

Topics

• Drug Evaluation
• Female
• Fluocinolone Acetonide (analogs & derivatives)
• Fluocinonide (administration & dosage)
• Humans
• Male
• Middle Aged
• Ointments
• Skin Diseases (drug therapy)