Dysgerminoma of the ovary with hypercalcemia associated with elevated parathyroid hormone-related protein.

Abstract

The purpose of the present paper is to present a rare case of dysgerminoma of the ovary with hypercalcemia showing elevation of multiple serum tumor markers including parathyroid hormone-related protein (PTH-rP). An 18-year-old unmarried woman, with ovarian dysgerminoma showing hypercalcemia and elevated serum PTH-rP, received six courses of a combination chemotherapy consisting of bleomycin, etoposide and cisplatin after her first surgery, and had no evidence of recurrence approximately 30 months after completing the chemotherapy.

• Authors: H Inoue, Y Kikuchi, J Hirata, S Wada, K Seki, I Nagata
• Journal: Japanese journal of clinical oncology (Jpn J Clin Oncol) Vol. 25 Issue 3 Pg. 113-7 (Jun 1995) ISSN: 0368-2811 [Print] England
• PMID: 7596049 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Biomarkers, Tumor
• Neoplasm Proteins
• PTHLH protein, human
• Parathyroid Hormone-Related Protein
• Proteins

Topics

• Adolescent
• Biomarkers, Tumor (blood)
• Combined Modality Therapy
• Dysgerminoma (blood, complications, therapy)
• Female
• Humans
• Hypercalcemia (complications)
• Neoplasm Proteins (metabolism)
• Ovarian Neoplasms (blood, complications, therapy)
• Parathyroid Hormone-Related Protein
• Proteins (metabolism)