HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Mucin histochemistry of ovarian mucinous cystadenomas expressing gastrointestinal characteristics.

Abstract
Fifty-four cases of ovarian mucinous cystadenoma, including two cases containing ciliated cells representing the müllerian epithelial origin, one case admixed with serous adenoma component and six cases associated with mature teratoma, were examined for the demonstration of gastrointestinal characteristics using periodic acid-Schiff, alcian blue, galactose oxidase-Schiff, paradoxycal concanavalin A (ConA), Grimelius and Fontana-Masson stains. Of 41 endocervical-type mucinous cystadenomas not associated with teratoma, 34 cases (83%) showed ConA positivity, expressing gastrointestinal characteristics. As both cases with ciliated cells and the case with serous adenoma component exhibited ConA positivity, the ovarian surface epithelium is supposed to undergo mucinous metaplasia possessing gastrointestinal characteristics. As to the histogenesis of the ovarian mucinous tumors, the metaplasia theory is suggested.
AuthorsK Nomura
JournalPathology international (Pathol Int) Vol. 45 Issue 6 Pg. 430-5 (Jun 1995) ISSN: 1320-5463 [Print] Australia
PMID7581934 (Publication Type: Journal Article)
Chemical References
  • Mucins
Topics
  • Adult
  • Aged
  • Cystadenoma, Mucinous (chemistry, pathology)
  • Cystadenoma, Serous (chemistry, pathology)
  • Female
  • Gastrointestinal Neoplasms (pathology)
  • Humans
  • Middle Aged
  • Mucins (analysis)
  • Neoplasms, Second Primary (chemistry, pathology)
  • Ovarian Neoplasms (chemistry, pathology)
  • Teratoma (chemistry, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: