Successful treatment with ganciclovir of presumed Epstein-Barr meningo-encephalitis following bone marrow transplant.

Abstract

Epstein-Barr virus-specific polymerase chain reaction was used to diagnose EBV-meningo-encephalitis in a bone marrow transplant recipient. The patient made complete recovery with ganciclovir treatment. Pitfalls in diagnosis with EBV-PCR and the potential therapeutic efficacy of ganciclovir in EBV infections are discussed.

• Authors: P L Dellemijn, A Brandenburg, H G Niesters, M J van den Bent, P H Rothbarth, L T Vlasveld
• Journal: Bone marrow transplantation (Bone Marrow Transplant) Vol. 16 Issue 2 Pg. 311-2 (Aug 1995) ISSN: 0268-3369 [Print] England
• PMID: 7581154 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiviral Agents
• Ganciclovir

Topics

• Antiviral Agents (therapeutic use)
• Bone Marrow Transplantation (adverse effects)
• Female
• Ganciclovir (therapeutic use)
• Herpesviridae Infections (drug therapy)
• Herpesvirus 4, Human
• Humans
• Meningoencephalitis (drug therapy)
• Middle Aged
• Polymerase Chain Reaction
• Tumor Virus Infections (drug therapy)