[Outcomes of effective treatment of cases of metastatic liver tumors by intra-arterial infusion chemotherapy].

Abstract

We studied the prognoses of unresectable liver tumors, including 31 colorectal cancers and 10 gastric cancers treated by intra-arterial infusion chemotherapy using an implantable reservoir. Adriamycin, epirubicin, or cisplatin were administered intermittently early on. Cisplatin and 5-FU combined therapy were given later. In nine with colorectal metastases and six with gastric metastases, metastatic lesions decreased, and in 4 patients with metastatic lesions could be resected. But in many patients, hepatic and other organ recurrences were observed. We need to try many other treatments.

• Authors: T Koizumi, K Mori, M Osaku, Y Watahiki, M Hojyo, A Kosaka, H Maruo
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 22 Issue 11 Pg. 1573-6 (Sep 1995) ISSN: 0385-0684 [Print] Japan
• PMID: 7574763 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Epirubicin
• Doxorubicin
• Cisplatin
• Fluorouracil

Topics

• Adenocarcinoma (drug therapy, secondary)
• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cisplatin (administration & dosage)
• Colonic Neoplasms (pathology)
• Doxorubicin (administration & dosage)
• Epirubicin (administration & dosage)
• Female
• Fluorouracil (administration & dosage)
• Humans
• Infusion Pumps, Implantable
• Infusions, Intra-Arterial
• Liver Neoplasms (drug therapy, secondary)
• Male
• Middle Aged
• Stomach Neoplasms (pathology)
• Treatment Outcome